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Diagnostic Endoscopy. At-Home Test. Related Conditions. Gluten Sensitivity. Refractory Celiac Disease. Gluten-Related Disorders. Dermatitis Herpetiformis.
Research News. Research Email Sign Up. Research Interviews. Drug Development. Drug Development Pipeline. Clinical Trials. Our Science Plan. Funding Opportunities. Patient Recruitment. Our Science Team. In fact, there's a huge difference in the number of females and males who have the condition: several studies have found that it's twice as likely in girls and women.
It's not clear why this is. Some researchers have speculated that women are more likely than men to seek help from a doctor for medical issues men may tend to tough them out, especially young adult men.
But although men's reluctance to see a doctor may be a factor in these different diagnosis rates, it doesn't completely explain the difference. Celiac disease is an autoimmune condition a condition where your body's immune system mistakenly attacks your own tissue , and women generally have a much higher risk of autoimmune conditions than men. As with celiac disease, scientists haven't been able to completely explain the overall higher risk of autoimmune conditions in women, either.
Men and women who have the condition tend to show different celiac disease symptoms. Women may have infertility or problems with their periods as their first sign of celiac disease. The rate of miscarriage is also higher among women with celiac disease as is the incidence of low birth-rate six times higher and the risk of intrauterine growth retardation. The following symptoms have also been found to be more prevalent in women than men:.
Men, meanwhile, are more likely to have the "classic" celiac symptoms of diarrhea and weight loss when they're first diagnosed with the condition, but this may be because they're more likely to wait to see a doctor. Men with celiac disease also are more likely than women to be underweight, to have reflux and iron deficiency anemia , and to have the itchy gluten-caused rash called dermatitis herpetiformis.
Men with celiac disease have also been found to experience reproductive problems, including hypogonadism, sexual dysfunction, or poor semen quality, resulting in increased infertility. Following a gluten-free diet can be challenging. We're here to help. Sign up and receive our free recipe guide for delicious gluten-free meals! Shah S, Leffler D. Womens Health Lond. Influence of gender on the clinical presentation and associated diseases in adults with celiac disease.
Gac Med Mex. Villi absorb vitamins, minerals and other nutrients from the food you eat. If your villi are damaged, you can't get enough nutrients, no matter how much you eat. Some people with celiac disease don't respond to what they consider to be a gluten-free diet.
Nonresponsive celiac disease is often due to contamination of the diet with gluten. Working with a dietitian can help you learn how to avoid all gluten. In rare instances, the intestinal injury of celiac disease doesn't respond to a strict gluten-free diet. This is known as refractory celiac disease.
If you still have signs and symptoms after following a gluten-free diet for six months to one year, you might need further testing to look for other explanations for your symptoms. Celiac disease care at Mayo Clinic. Mayo Clinic does not endorse companies or products.
Advertising revenue supports our not-for-profit mission. This content does not have an English version. This content does not have an Arabic version. Overview Celiac disease Open pop-up dialog box Close. Celiac disease Your small intestine is lined with tiny hairlike projections called villi, which absorb vitamins, minerals and other nutrients from the food you eat. Email address. First Name let us know your preferred name. Last Name. Thank you for subscribing Your in-depth digestive health guide will be in your inbox shortly.
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